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Pro-oxidant Induced DNA Damage in Human Lymphoblastoid Cells: Homeostatic Mechanisms of Genotoxic Tolerance

Oxidative stress contributes to many disease etiologies including ageing, neurodegeneration, and cancer, partly through DNA damage induction (genotoxicity). Understanding the i nteractions of free radicals with DNA is fundamental to discern mutation risks. In genetic toxicology, regulatory authoriti...

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Detalhes bibliográficos
Main Authors: Seager, Anna L., Shah, Ume-Kulsoom, Mikhail, Jane M., Nelson, Bryant C., Marquis, Bryce J., Doak, Shareen H., Johnson, George E., Griffiths, Sioned M., Carmichael, Paul L., Scott, Sharon J., Scott, Andrew D., Jenkins, Gareth J. S.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3493188/
https://ncbi.nlm.nih.gov/pubmed/22539617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfs152
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