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Evaluation of the automated MicroFlow(®) and Metafer™ platforms for high-throughput micronucleus scoring and dose response analysis in human lymphoblastoid TK6 cells

The use of manual microscopy for the scoring of chromosome damage in the in vitro micronucleus assay is often associated with user subjectivity. This level of subjectivity can be reduced by using automated platforms, which have added value of faster with high-throughput and multi-endpoint capabiliti...

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Detalhes bibliográficos
Publicado no:Arch Toxicol
Main Authors: Verma, Jatin R., Rees, Benjamin J., Wilde, Eleanor C., Thornton, Catherine A., Jenkins, Gareth J.S., Doak, Shareen H., Johnson, George E.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5489585/
https://ncbi.nlm.nih.gov/pubmed/27942789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00204-016-1903-8
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