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Evaluation of the automated MicroFlow(®) and Metafer™ platforms for high-throughput micronucleus scoring and dose response analysis in human lymphoblastoid TK6 cells

The use of manual microscopy for the scoring of chromosome damage in the in vitro micronucleus assay is often associated with user subjectivity. This level of subjectivity can be reduced by using automated platforms, which have added value of faster with high-throughput and multi-endpoint capabiliti...

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Publicat a:Arch Toxicol
Autors principals: Verma, Jatin R., Rees, Benjamin J., Wilde, Eleanor C., Thornton, Catherine A., Jenkins, Gareth J.S., Doak, Shareen H., Johnson, George E.
Format: Artigo
Idioma:Inglês
Publicat: Springer Berlin Heidelberg 2016
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5489585/
https://ncbi.nlm.nih.gov/pubmed/27942789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00204-016-1903-8
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