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RAPID detection of gene–gene interactions in genome-wide association studies
Motivation: In complex disorders, independently evolving locus pairs might interact to confer disease susceptibility, with only a modest effect at each locus. With genome-wide association studies on large cohorts, testing all pairs for interaction confers a heavy computational burden, and a loss of...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Oxford University Press
2010
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3493125/ https://ncbi.nlm.nih.gov/pubmed/20871107 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btq529 |
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