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Silencing of the polyamine catabolic key enzyme SSAT prevents CDK inhibitor-induced apoptosis in Caco-2 colon cancer cells

Roscovitine and purvalanol are purine derivative cyclin-dependent kinase (CDK) inhibitors that induce apoptosis in various types of cancer cells. However, their impact on the apoptotic cell death mechanism requires further elucidation. Natural polyamines putrescine, spermidine and spermine play esse...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: ÇOKER, A., ARISAN, E.D., PALAVAN-ÜNSAL, N.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: D.A. Spandidos 2012
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3493106/
https://ncbi.nlm.nih.gov/pubmed/22294330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2012.768
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