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The SYK side of TLR4: signalling mechanisms in response to LPS and minimally oxidized LDL

Spleen tyrosine kinase (SYK) is the best known for its involvement in immune receptor signalling, mediated by binding of SYK tandem Src-homology 2 domains to tandem phosphotyrosine in immunoreceptor tyrosine-based activation motifs (ITAMs). ITAM adaptors or ITAM-containing receptor tails mediate sig...

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Detalhes bibliográficos
Main Authors: Miller, Yury I, Choi, Soo-Ho, Wiesner, Philipp, Bae, Yun Soo
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3492981/
https://ncbi.nlm.nih.gov/pubmed/22776094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2012.02097.x
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