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Ions, equations and electrons: the evolving role of computer simulations in cardiac electrophysiology safety evaluations
Reliable preclinical cardiac safety evaluations of drug candidates are essential for selecting the best therapeutic agents. Advanced automated patch clamp technologies now allow for characterizing drug effects on multiple cardiac currents, enabling subsequent simulations of integrated electrophysiol...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Blackwell Publishing Ltd
2012
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3492976/ https://ncbi.nlm.nih.gov/pubmed/22776041 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2012.02096.x |
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