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Upfront Bevacizumab and Temozolomide or Fotemustine before Radiotherapy for Patients with Glioblastoma and Severe Neurological Impairment at Diagnosis

Unresectable glioblastomas with severe neurological impairment at diagnosis have a poor prognosis. The conventional approach using a temozolomide-based chemoradiotherapy has limited efficiency on patients in the RTOG RPA V–VI classes. The activity of the antiangiogenic monoclonal antibody bevacizuma...

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Detalhes bibliográficos
Main Authors: Bihan, Celina, Foscolo, Sylvain, Boone, Mathieu, Blonski, Marie, Coutte, Alexandre, Darlix, Amélie, Beauchesne, Patrick, Lefranc, Michel, Lorgis, Veronique, Taillandier, Luc, Chauffert, Bruno
Formato: Artigo
Idioma:Inglês
Publicado em: S. Karger AG 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3492967/
https://ncbi.nlm.nih.gov/pubmed/23139667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000343139
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