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Permeability of ergot alkaloids across the blood-brain barrier in vitro and influence on the barrier integrity

SCOPE: Ergot alkaloids are secondary metabolites of Claviceps spp. and they have been in the focus of research for many years. Experiments focusing on ergotamine as a former migraine drug referring to the ability to reach the brain revealed controversial results. The question to which extent ergot a...

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Autors principals: Mulac, Dennis, Hüwel, Sabine, Galla, Hans-Joachim, Humpf, Hans-Ulrich
Format: Artigo
Idioma:Inglês
Publicat: WILEY-VCH Verlag 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3492916/
https://ncbi.nlm.nih.gov/pubmed/22147614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mnfr.201100431
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