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Epigenetic regulation of cancer stem cells in liver cancer: Current concepts and clinical implications

The two dominant models of carcinogenesis postulate stochastic (clonal evolution) or hierarchic organization of tumor (cancer stem cell model). According to the latter, at the germinal center of tumor evolution is a cancer stem cell (CSC) which, similar to normal adult stem cells, possesses the capa...

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Détails bibliographiques
Auteurs principaux: Marquardt, J.U., Factor, V.M., Thorgeirsson, S.S.
Format: Artigo
Langue:Inglês
Publié: 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3492877/
https://ncbi.nlm.nih.gov/pubmed/20646772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jhep.2010.05.003
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