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The response of PKD1L3 / PKD2L1 to acid stimuli is inhibited by capsaicin and its pungent analogs

Polycystic kidney disease (PKD) 2L1 protein is a member of the transient receptor potential (TRP) ion channel family. In circumvallate and foliate papillae, PKD2L1 is coexpressed with PKD1L3. PKD2L1 and PKD1L3 interact through their transmembrane domain and the resulting heteromer PKD1L3/PKD2L1 owns...

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Detalhes bibliográficos
Main Authors: Ishii, Sho, Kurokawa, Azusa, Kishi, Mikiya, Yamagami, Keigo, Okada, Shinji, Ishimaru, Yoshiro, Misaka, Takumi
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3492849/
https://ncbi.nlm.nih.gov/pubmed/22420714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1742-4658.2012.08566.x
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