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Nucleotide insertion in the anticodon loop of a glycine transfer RNA causes missense suppression.

We have determined the nucleotide sequences of two unusual UGG-suppressing glycine tRNAs from Escherichia coli and, as a result, have discovered a new mechanism for the generation of missense suppressors. The suppressor tRNAs translate UGG but not UGA. Each arose as a consequence of spontaneous muta...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Prather, N E, Murgola, E J, Mims, B H
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1981
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC349276/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7038678/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.78.12.7408
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