Suppression of a double missense mutation by a mutant tRNA(Phe) in Escherichia coli.

We report here the isolation of a mutant tRNAPhe that suppresses a double missense auxotrophic mutation in trpA of Escherichia coli, trpA218. The doubly mutant protein product differs from wild-type TrpA by the replacements of Phe22 by Leu and Gly211 by Ser. A partial revertant TrpA phenotype can be...

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Detalhes bibliográficos

Publicado no:	Nucleic Acids Res
Principais autores:	Pages, D, Hijazi, K, Murgola, E J, Finelli, J, Buckingham, R H
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Oxford University Press 1991
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC333723/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2017368/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/19.4.867
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