A role for CTCF and cohesin in subtelomere chromatin organization, TERRA transcription, and telomere end protection

The contribution of human subtelomeric DNA and chromatin organization to telomere integrity and chromosome end protection is not yet understood in molecular detail. Here, we show by ChIP-Seq that most human subtelomeres contain a CTCF- and cohesin-binding site within ∼1–2 kb of the TTAGGG repeat tra...

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Detalhes bibliográficos
Main Authors: Deng, Zhong, Wang, Zhuo, Stong, Nick, Plasschaert, Robert, Moczan, Aliah, Chen, Horng-Shen, Hu, Sufeng, Wikramasinghe, Priyankara, Davuluri, Ramana V, Bartolomei, Marisa S, Riethman, Harold, Lieberman, Paul M
Formato: Artigo
Idioma:Inglês
Publicado em: European Molecular Biology Organization 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3492729/
https://ncbi.nlm.nih.gov/pubmed/23010778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2012.266
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