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Chd1 chromatin remodelers maintain nucleosome organization and repress cryptic transcription

Chromatin organization is essential for defining transcription units and maintaining genomic integrity in eukaryotes. In this study, we found that deletion of the Schizosaccharomyces pombe Chd1 chromatin remodelers, hrp1 and hrp3, causes strong, genome-wide accumulation of antisense transcripts. Nuc...

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Detalhes bibliográficos
Main Authors: Hennig, Bianca P, Bendrin, Katja, Zhou, Yang, Fischer, Tamás
Formato: Artigo
Idioma:Inglês
Publicado em: European Molecular Biology Organization 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3492713/
https://ncbi.nlm.nih.gov/pubmed/23032292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2012.146
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