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Co-localization of NANOG and OCT4 in human pre-implantation embryos and in human embryonic stem cells

PURPOSE: NANOG and OCT4 are required for the maintenance of pluripotency in embryonic stem cells (ESCs). These proteins are also expressed in the inner cell mass (ICM) of the mouse pre-implantation embryo. METHODS: Immunohistochemistry was used to show the presence of NANOG and OCT4 protein, and in...

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Detalhes bibliográficos
Main Authors: Hambiliki, Fredwell, Ström, Susanne, Zhang, Pu, Stavreus-Evers, Anneli
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3492569/
https://ncbi.nlm.nih.gov/pubmed/22743827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10815-012-9824-9
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