A carregar...
Crystal structure of adenovirus E3-19K bound to HLA-A2 reveals mechanism for immunomodulation
E3-19K binds to and retains MHC class I molecules in the endoplasmic reticulum, suppressing anti-Adenovirus (Ad) activities of T-cells. We determined the structure of the Ad serotype 2 (Ad2, species C) E3-19K–HLA-A2 complex to 1.95 Å resolution. Ad2 E3-19K binds to the N-terminus of the HLA-A2 groov...
Na minha lista:
| Main Authors: | , , |
|---|---|
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3492506/ https://ncbi.nlm.nih.gov/pubmed/23042604 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.2396 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|