Paradoxical Impact of Two Folate Receptors, FRα and RFC, in Ovarian Cancer: Effect on Cell Proliferation, Invasion and Clinical Outcome

Despite being an essential vitamin, folate has been implicated to enhance tumor growth, as evidenced by reports on overexpression of folate receptor alpha (FRα) in carcinomas. The role of another folate transporter, reduced folate carrier (RFC), is largely unknown. This study investigated the roles...

詳細記述

保存先:
書誌詳細
主要な著者: Siu, Michelle K. Y., Kong, Daniel S. H., Chan, Hoi Yan, Wong, Esther S. Y., Ip, Philip P. C., Jiang, LiLi, Ngan, Hextan Y. S., Le, Xiao-Feng, Cheung, Annie N. Y.
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2012
主題:
Research Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3492371/
https://ncbi.nlm.nih.gov/pubmed/23144806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0047201
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