Paradoxical Impact of Two Folate Receptors, FRα and RFC, in Ovarian Cancer: Effect on Cell Proliferation, Invasion and Clinical Outcome

Despite being an essential vitamin, folate has been implicated to enhance tumor growth, as evidenced by reports on overexpression of folate receptor alpha (FRα) in carcinomas. The role of another folate transporter, reduced folate carrier (RFC), is largely unknown. This study investigated the roles...

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Detalhes bibliográficos
Main Authors: Siu, Michelle K. Y., Kong, Daniel S. H., Chan, Hoi Yan, Wong, Esther S. Y., Ip, Philip P. C., Jiang, LiLi, Ngan, Hextan Y. S., Le, Xiao-Feng, Cheung, Annie N. Y.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3492371/
https://ncbi.nlm.nih.gov/pubmed/23144806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0047201
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