p21-activated kinase 4 regulates ovarian cancer cell proliferation, migration, and invasion and contributes to poor prognosis in patients

Ovarian cancer is a lethal gynecological malignancy, and to improve survival, it is important to identify novel prognostic and therapeutic targets. In this study, we present a role for p21-activated kinase 4 (Pak4) in ovarian cancer progression. We show a significant association between increased ex...

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Autori principali: Siu, Michelle K. Y., Chan, Hoi Yan, Kong, Daniel S. H., Wong, Esther S. Y., Wong, Oscar G. W., Ngan, Hextan Y. S., Tam, Kar Fai, Zhang, Hongquan, Li, Zhilun, Chan, Queeny K. Y., Tsao, Sai Wah, Strömblad, Staffan, Cheung, Annie N. Y.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2010
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2972956/
https://ncbi.nlm.nih.gov/pubmed/20926745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0907481107
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