p21-activated kinase 4 regulates ovarian cancer cell proliferation, migration, and invasion and contributes to poor prognosis in patients

Ovarian cancer is a lethal gynecological malignancy, and to improve survival, it is important to identify novel prognostic and therapeutic targets. In this study, we present a role for p21-activated kinase 4 (Pak4) in ovarian cancer progression. We show a significant association between increased ex...

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Détails bibliographiques
Auteurs principaux: Siu, Michelle K. Y., Chan, Hoi Yan, Kong, Daniel S. H., Wong, Esther S. Y., Wong, Oscar G. W., Ngan, Hextan Y. S., Tam, Kar Fai, Zhang, Hongquan, Li, Zhilun, Chan, Queeny K. Y., Tsao, Sai Wah, Strömblad, Staffan, Cheung, Annie N. Y.
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2010
Sujets:
Biological Sciences
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2972956/
https://ncbi.nlm.nih.gov/pubmed/20926745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0907481107
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