Enhanced Antitumor Efficacy and Reduced Systemic Toxicity of Sulfatide-Containing Nanoliposomal Doxorubicin in a Xenograft Model of Colorectal Cancer

Sulfatide is a glycosphingolipid known to interact with several extracellular matrix proteins, such as tenascin-C which is overexpressed in many types of cancer including that of the colon. In view of the limited success of chemotherapy in colorectal cancer and high toxicity of doxorubicin (DOX), a...

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Hlavní autoři: Lin, Jia, Yu, Yan, Shigdar, Sarah, Fang, Ding Zhi, Du, Jun Rong, Wei, Ming Q., Danks, Andrew, Liu, Ke, Duan, Wei
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2012
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3492268/
https://ncbi.nlm.nih.gov/pubmed/23145140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0049277
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