Enhanced Antitumor Efficacy and Reduced Systemic Toxicity of Sulfatide-Containing Nanoliposomal Doxorubicin in a Xenograft Model of Colorectal Cancer

Sulfatide is a glycosphingolipid known to interact with several extracellular matrix proteins, such as tenascin-C which is overexpressed in many types of cancer including that of the colon. In view of the limited success of chemotherapy in colorectal cancer and high toxicity of doxorubicin (DOX), a...

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Detalhes bibliográficos
Main Authors: Lin, Jia, Yu, Yan, Shigdar, Sarah, Fang, Ding Zhi, Du, Jun Rong, Wei, Ming Q., Danks, Andrew, Liu, Ke, Duan, Wei
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3492268/
https://ncbi.nlm.nih.gov/pubmed/23145140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0049277
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