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Accumulation of instability in serial differentiation and reprogramming of parthenogenetic human cells
Human leukocyte antigen-homozygous parthenogenetic stem cells (pSC) could provide a source of progenitors for regenerative medicine, lowering the need for immune suppression in patients. However, the high level of homozygosis and the lack of a paternal genome might pose a safety challenge for their...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3491960/ https://ncbi.nlm.nih.gov/pubmed/22547223 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/dds168 |
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