Interleukin-13 protects from atherosclerosis and modulates plaque composition by skewing the macrophage phenotype

Atherosclerotic lesions are characterized by the accumulation of oxidized LDL (OxLDL) and the infiltration of macrophages and T cells. Cytokine expression in the microenvironment of evolving lesions can profoundly contribute to plaque development. While the pro-atherogenic effect of T helper (Th) 1...

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Autores principales: Cardilo-Reis, Larissa, Gruber, Sabrina, Schreier, Sabine M, Drechsler, Maik, Papac-Milicevic, Nikolina, Weber, Christian, Wagner, Oswald, Stangl, Herbert, Soehnlein, Oliver, Binder, Christoph J
Formato: Artigo
Lenguaje:Inglês
Publicado: WILEY-VCH Verlag 2012
Materias:
Research Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3491837/
https://ncbi.nlm.nih.gov/pubmed/23027612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/emmm.201201374
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