5-HT(6) receptor recruitment of mTOR as a mechanism for perturbed cognition in schizophrenia

Cognitive deficits in schizophrenia severely compromise quality of life and are poorly controlled by current antipsychotics. While 5-HT(6) receptor blockade holds special promise, molecular substrates underlying their control of cognition remain unclear. Using a proteomic strategy, we show that 5-HT...

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Bibliografski detalji
Glavni autori: Meffre, Julie, Chaumont-Dubel, Séverine, Mannoury la Cour, Clotilde, Loiseau, Florence, Watson, David J G, Dekeyne, Anne, Séveno, Martial, Rivet, Jean-Michel, Gaven, Florence, Déléris, Paul, Hervé, Denis, Fone, Kevin C F, Bockaert, Joël, Millan, Mark J, Marin, Philippe
Format: Artigo
Jezik:Inglês
Izdano: WILEY-VCH Verlag 2012
Teme:
Research Articles
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3491835/
https://ncbi.nlm.nih.gov/pubmed/23027611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/emmm.201201410
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