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Quantitative Phosphoproteomics Unravels Biased Phosphorylation of Serotonin 2A Receptor at Ser(280) by Hallucinogenic versus Nonhallucinogenic Agonists
The serotonin 5-HT(2A) receptor is a primary target of psychedelic hallucinogens such as lysergic acid diethylamine, mescaline, and psilocybin, which reproduce some of the core symptoms of schizophrenia. An incompletely resolved paradox is that only some 5-HT(2A) receptor agonists exhibit hallucinog...
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| Main Authors: | , , , , , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
The American Society for Biochemistry and Molecular Biology
2014
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4014284/ https://ncbi.nlm.nih.gov/pubmed/24637012 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M113.036558 |
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