Base-pair substitution hotspots in GAG and GCG nucleotide sequences in Escherichia coli K-12 induced by cis-diamminedichloroplatinum (II).

Cell killing and mutation induction by cis- and trans-Pt(NH3)2Cl2 in Escherichia coli were examined by studying forward mutagenesis in the lacI gene in cells with different repair capacities. Survival experiments showed that repair-proficient cells were slightly more sensitive for the cis isomer tha...

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Detalhes bibliográficos
Main Authors: Brouwer, J, van de Putte, P, Fichtinger-Schepman, A M, Reedijk, J
Formato: Artigo
Idioma:Inglês
Publicado em: 1981
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC349183/
https://ncbi.nlm.nih.gov/pubmed/7031665
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