Preventing acute gut wall damage in infectious diarrhoeas with glycosylated dendrimers

Intestinal pathogens use the host's excessive inflammatory cytokine response, designed to eliminate dangerous bacteria, to disrupt epithelial gut wall integrity and promote their tissue invasion. We sought to develop a non-antibiotic-based approach to prevent this injury. Molecular docking stud...

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Detalhes bibliográficos
Main Authors: Teo, Ian, Toms, Steve M, Marteyn, Benoit, Barata, Teresa S, Simpson, Peter, Johnston, Karen A, Schnupf, Pamela, Puhar, Andrea, Bell, Tracey, Tang, Chris, Zloh, Mire, Matthews, Steve, Rendle, Phillip M, Sansonetti, Philippe J, Shaunak, Sunil
Formato: Artigo
Idioma:Inglês
Publicado em: WILEY-VCH Verlag 2012
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3491821/
https://ncbi.nlm.nih.gov/pubmed/22887873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/emmm.201201290
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