Carregando...
Partially glycosylated dendrimers block MD-2 and prevent TLR4-MD-2-LPS complex mediated cytokine responses.
The crystal structure of the TLR4-MD-2-LPS complex responsible for triggering powerful pro-inflammatory cytokine responses has recently become available. Central to cell surface complex formation is binding of lipopolysaccharide (LPS) to soluble MD-2. We have previously shown, in biologically based...
Na minha lista:
| Principais autores: | , , , , |
|---|---|
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science (PLoS)
2011-06-01
|
| coleção: | PLoS Computational Biology |
| Acesso em linha: | http://europepmc.org/articles/PMC3127813?pdf=render |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|