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Morphologic study of the internalization of a lysosomal enzyme by the mannose 6-phosphate receptor in cultured Chinese hamster ovary cells.

The binding and internalization of a model lysosomal enzyme, beta-galactosidase, was visualized by use of rabbit anti-beta-galactosidase and goat anti-rabbit IgG; the second antibody was labeled with rhodamine or fluorescein (for detection by fluorescence) or with horseradish peroxidase (for electro...

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Main Authors: Willingham, M C, Pastan, I H, Sahagian, G G, Jourdian, G W, Neufeld, E F
格式: Artigo
語言:Inglês
出版: 1981
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC349174/
https://ncbi.nlm.nih.gov/pubmed/6273898
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