A novel role for lipid droplets in the organismal antibacterial response

We previously discovered histones bound to cytosolic lipid droplets (LDs); here we show that this forms a cellular antibacterial defense system. Sequestered on droplets under normal conditions, in the presence of bacterial lipopolysaccharide (LPS) or lipoteichoic acid (LTA), histones are released fr...

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Detalhes bibliográficos
Main Authors: Anand, Preetha, Cermelli, Silvia, Li, Zhihuan, Kassan, Adam, Bosch, Marta, Sigua, Robilyn, Huang, Lan, Ouellette, Andre J, Pol, Albert, Welte, Michael A, Gross, Steven P
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2012
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3491588/
https://ncbi.nlm.nih.gov/pubmed/23150794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.00003
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