Reducing Available Soluble β-Amyloid Prevents Progression of Cerebral Amyloid Angiopathy in Transgenic Mice

Cerebral amyloid angiopathy (CAA), the accumulation of β-amyloid (Aβ) in the walls of leptomeningeal and cortical blood vessels of the brain, is a major cause of intracerebral hemorrhage and cognitive impairment, and is commonly associated with Alzheimer disease (AD). CAA progression, as measured in...

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Main Authors: Gregory, Julia L., Prada, Claudia M., Fine, Sara J., Garcia-Alloza, Monica, Betensky, Rebecca A., Arbel-Ornath, Michal, Greenberg, Steven M., Bacskai, Brian J., Frosch, Matthew P.
Format: Artigo
Sprog:Inglês
Udgivet: 2012
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3491571/
https://ncbi.nlm.nih.gov/pubmed/23095848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/NEN.0b013e3182729845
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