Matrix metalloproteinase inhibition reduces oxidative stress associated with cerebral amyloid angiopathy in vivo in transgenic mice

Cerebral amyloid angiopathy (CAA), characterized by extracellular β-amyloid peptide (Aβ) deposits in vessel walls, is present in the majority of cases of Alzheimer disease and is a major cause of hemorrhagic stroke. Although the molecular pathways activated by vascular Aβ are poorly understood, extr...

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Main Authors: Garcia-Alloza, Monica, Prada, Claudia, Lattarulo, Carli, Fine, Sara, Borrelli, Laura A., Betensky, Rebecca, Greenberg, Steven M., Frosch, Matthew P., Bacskai, Brian J.
Formato: Artigo
Idioma:Inglês
Publicado: 2009
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3281746/
https://ncbi.nlm.nih.gov/pubmed/19457117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1471-4159.2009.06096.x
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