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The histone variant macroH2A1.1 is recruited to DSBs through a mechanism involving PARP1
The repair of DNA double-strand breaks (DSBs) requires remodeling of the local chromatin architecture to allow the repair machinery to access sites of damage. Here, we report that the histone variant macroH2A1.1 is recruited to DSBs. Cells lacking macroH2A1 have defective recruitment of 53BP1, defec...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2012
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3491562/ https://ncbi.nlm.nih.gov/pubmed/23031826 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2012.09.030 |
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