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Modified SH2 domain to phototrap and identify phosphotyrosine proteins from subcellular sites within cells
Spatial regulation of tyrosine phosphorylation is important for many aspects of cell biology. However, phosphotyrosine accounts for less than 1% of all phosphorylated substrates, and it is typically a very transient event in vivo. These factors complicate the identification of key tyrosine kinase su...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3491470/ https://ncbi.nlm.nih.gov/pubmed/23027962 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1207358109 |
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