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HCF-1 self-association via an interdigitated Fn3 structure facilitates transcriptional regulatory complex formation
Host-cell factor 1 (HCF-1) is an unusual transcriptional regulator that undergoes a process of proteolytic maturation to generate N- (HCF-1(N)) and C- (HCF-1(C)) terminal subunits noncovalently associated via self-association sequence elements. Here, we present the crystal structure of the self-asso...
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| 主要な著者: | , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
National Academy of Sciences
2012
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3491465/ https://ncbi.nlm.nih.gov/pubmed/23045687 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1208378109 |
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