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IL-6 Trans-Signaling via the Soluble IL-6 Receptor: Importance for the Pro-Inflammatory Activities of IL-6

Interleukin-6 (IL-6) is a cytokine with many activities. It has functions in the regulation of the immune system and the nervous system. Furthermore, IL-6 is involved in liver regeneration and in the metabolic control of the body. On target cells, IL-6 binds to an 80 kDa IL-6 receptor (IL-6R). The c...

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Detalhes bibliográficos
Autor principal: Rose-John, Stefan
Formato: Artigo
Idioma:Inglês
Publicado em: Ivyspring International Publisher 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3491447/
https://ncbi.nlm.nih.gov/pubmed/23136552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijbs.4989
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