The birth of the Epitranscriptome: deciphering the function of RNA modifications

Recent studies have found methyl-6-adenosine in thousands of mammalian genes, and this modification is most pronounced near the beginning of the 3' UTR. We present a perspective on current work and new single-molecule sequencing methods for detecting RNA base modifications.

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Bibliografiske detaljer
Main Authors: Saletore, Yogesh, Meyer, Kate, Korlach, Jonas, Vilfan, Igor D, Jaffrey, Samie, Mason, Christopher E
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2012
Fag:
Opinion
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3491402/
https://ncbi.nlm.nih.gov/pubmed/23113984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2012-13-10-175
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