Thyrotropin-releasing hormone exerts rapid nuclear effects to increase production of the primary prolactin mRNA transcript.

This report directly documents that a polypeptide hormone can regulate specific gene expression as a consequence of increasing the levels of a primary genomic transcript. The regulation and expression of the prolactin gene was studied in a cell line (GH4) derived from a rat pituitary tumor. These ce...

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Bibliographische Detailangaben
Hauptverfasser: Potter, E, Nicolaisen, A K, Ong, E S, Evans, R M, Rosenfeld, M G
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1981
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC349109/
https://ncbi.nlm.nih.gov/pubmed/6796963
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