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The Thyrotropin-Releasing Hormone Gene Is Regulated by Thyroid Hormone at the Level of Transcription in Vivo

The expression of the TRH gene in the paraventricular nucleus (PVH) of the hypothalamus is required for the normal production of thyroid hormone (TH) in rodents and humans. In addition, the regulation of TRH mRNA expression by TH, specifically in the PVH, ensures tight control of the set point of th...

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Autori principali: Sugrue, Michelle L., Vella, Kristen R., Morales, Crystal, Lopez, Marisol E., Hollenberg, Anthony N.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Endocrine Society 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2817611/
https://ncbi.nlm.nih.gov/pubmed/20032051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2009-0976
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