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Architectural layer-by-layer assembly of drug nanocapsules with PEGylated polyelectrolytes

150–200 nm diameter capsules containing 60–70 wt % of poorly soluble drugs, paclitaxel and camptothecin, were produced by layer-by-layer (LbL) assembly on drug nanocores in a solution containing uncharged stabilizers. Optimization of capsule shell architecture and thickness allowed for concentrated...

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Detalhes bibliográficos
Main Authors: Shutava, Tatsiana G., Pattekari, Pravin P., Arapov, Kirill A., Torchilin, Vladimir P., Lvov, Yuri M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3490450/
https://ncbi.nlm.nih.gov/pubmed/23144650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/C2SM25683E
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