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A general high-efficiency procedure for production of microcell hybrids.

The relative efficiency of microcell-mediated chromosome transfer vs. somatic cell hybridization has been determined. The prolonged mitotic arrest generally used to micronucleate donor cells also reduced the fusion efficiency to 1/10th-1/5th of that in whole cell hybridizations. Here we report an al...

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Veröffentlicht in:Proc Natl Acad Sci U S A
1. Verfasser: Fournier, R E
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 1981
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC349036/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6947234/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.78.10.6349
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