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Isolation of microcell hybrid clones containing retroviral vector insertions into specific human chromosomes.

We sought an efficient means to introduce specific human chromosomes into stable interspecific hybrid cells for applications in gene mapping and studies of gene regulation. A defective amphotropic retrovirus was used to insert the gene conferring G418 resistance (neo), a dominant selectable marker,...

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Detalhes bibliográficos
Main Authors: Lugo, T G, Handelin, B, Killary, A M, Housman, D E, Fournier, R E
Formato: Artigo
Idioma:Inglês
Publicado em: 1987
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC367898/
https://ncbi.nlm.nih.gov/pubmed/2823107
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