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Immunohistochemical expression of caspase-1 and -9, uncleaved caspase-3 and -6, cleaved caspase-3 and -6 as well as Bcl-2 in benign epithelium and cancer of the prostate

Activation of caspases is an essential prerequisite for induction of apoptosis. In many tumors caspases are down-regulated, while anti-apoptotic Bcl-2 is up-regulated. To elucidate their putative role in prostate cancer (PCa) we determined the expression of different caspases and Bcl-2 in benign pro...

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Detalhes bibliográficos
Main Authors: UMMANNI, RAMESH, LEHNIGK, ULRIKE, ZIMMERMANN, UWE, WOENCKHAUS, CHRISTIAN, WALTHER, REINHARD, GIEBEL, JÜRGEN
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3490333/
https://ncbi.nlm.nih.gov/pubmed/23136591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm_00000008
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