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Neuron-to-neuron transmission of α-synuclein fibrils through axonal transport
OBJECTIVE: The lesions of Parkinson's disease spread through the brain in a characteristic pattern that corresponds to axonal projections. Previous observations suggest that misfolded α-synuclein could behave as a prion, moving from neuron to neuron and causing endogenous α-synuclein to misfold...
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| Main Authors: | , , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3490229/ https://ncbi.nlm.nih.gov/pubmed/23109146 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ana.23747 |
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