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RhoA Mediates Flow-induced Endothelial Sprouting in a 3-D Tissue Analogue of Angiogenesis

Endothelial cells (ECs) integrate signals from the local microenvironment to guide their behaviour. RhoA is involved in vascular endothelial growth factor (VEGF) - driven angiogenesis, but its role in mechanotransduction during sprouting has not been established. Using dominant negative cell transfe...

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Détails bibliographiques
Auteurs principaux: Song, Jonathan W., Daubriac, Julien, Tse, Janet M., Bazou, Despina, Munn, Lance L.
Format: Artigo
Langue:Inglês
Publié: 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3490212/
https://ncbi.nlm.nih.gov/pubmed/23073300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c2lc40389g
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