Non-canonical TAF complexes regulate active promoters in human embryonic stem cells

The general transcription factor TFIID comprises the TATA-box-binding protein (TBP) and approximately 14 TBP-associated factors (TAFs). Here we find, unexpectedly, that undifferentiated human embryonic stem cells (hESCs) contain only six TAFs (TAFs 2, 3, 5, 6, 7 and 11), whereas following differenti...

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Detalhes bibliográficos
Main Authors: Maston, Glenn A, Zhu, Lihua Julie, Chamberlain, Lynn, Lin, Ling, Fang, Minggang, Green, Michael R
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2012
Assuntos:
Genes and Chromosomes
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3490149/
https://ncbi.nlm.nih.gov/pubmed/23150797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.00068
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