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Control of Embryonic Stem Cell Lineage Commitment by Core Promoter Factor, TAF3

Deciphering the molecular basis of pluripotency is fundamental to our understanding of development and embryonic stem cell function. Here we report that TAF3, a TBP-associated core promoter factor, is highly enriched in ES cells. TAF3 is required for endoderm lineage differentiation and prevents pre...

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Autori principali: Liu, Zhe, Scannell, Devin R., Eisen, Michael B., Tjian, Robert
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3191068/
https://ncbi.nlm.nih.gov/pubmed/21884934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2011.08.005
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