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A triple helix stabilizes the 3′ ends of long noncoding RNAs that lack poly(A) tails
The MALAT1 (metastasis-associated lung adenocarcinoma transcript 1) locus is misregulated in many human cancers and produces an abundant long nuclear-retained noncoding RNA. Despite being transcribed by RNA polymerase II, the 3′ end of MALAT1 is produced not by canonical cleavage/polyadenylation but...
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| 主要な著者: | , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Cold Spring Harbor Laboratory Press
2012
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3489998/ https://ncbi.nlm.nih.gov/pubmed/23073843 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.204438.112 |
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