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Isolation of the Escherichia coli leader peptidase gene and effects of leader peptidase overproduction in vivo.

The only covalent modifications known to accompany protein insertion into membranes or protein secretion are glycosylation and the proteolytic removal of an NH2-terminal leader (signal) sequence. This latter reaction is catalyzed by leader peptidase, a constitutive, membrane-bound proteinase. We now...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Date, T, Wickner, W
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1981
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC348986/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6273848/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.78.10.6106
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