The A736V TMPRSS6 Polymorphism Influences Hepatic Iron Overload in Nonalcoholic Fatty Liver Disease

BACKGROUND & AIMS: Hepatic iron accumulation due to altered trafficking is frequent in patients with nonalcoholic fatty liver disease (NAFLD), and is associated with more severe liver damage and hepatocellular carcinoma. The p.Ala736Val TMPRSS6 variant influences iron metabolism regulating the t...

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Hauptverfasser: Valenti, Luca, Rametta, Raffaela, Dongiovanni, Paola, Motta, Benedetta M., Canavesi, Elena, Pelusi, Serena, Pulixi, Edoardo A., Fracanzani, Anna L., Fargion, Silvia
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2012
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3489825/
https://ncbi.nlm.nih.gov/pubmed/23144979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0048804
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