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The A736V TMPRSS6 Polymorphism Influences Hepatic Iron Overload in Nonalcoholic Fatty Liver Disease

BACKGROUND & AIMS: Hepatic iron accumulation due to altered trafficking is frequent in patients with nonalcoholic fatty liver disease (NAFLD), and is associated with more severe liver damage and hepatocellular carcinoma. The p.Ala736Val TMPRSS6 variant influences iron metabolism regulating the t...

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Main Authors: Valenti, Luca, Rametta, Raffaela, Dongiovanni, Paola, Motta, Benedetta M., Canavesi, Elena, Pelusi, Serena, Pulixi, Edoardo A., Fracanzani, Anna L., Fargion, Silvia
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3489825/
https://ncbi.nlm.nih.gov/pubmed/23144979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0048804
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